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Peer-reviewed veterinary case report

Horse with chronic weight loss diagnosed with multiple myeloma

By Markel, M D & Dorr, T E·Published in Journal of the American Veterinary Medical Association·1986·View original on PubMed

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Original publication title: Multiple myeloma in a horse.

Species:
horse
LymphomaAppetite & weightHorses

Plain-English summary

A 22-year-old Arabian mare was diagnosed with multiple myeloma, a type of cancer that affects plasma cells in the blood. She had been losing weight for a long time, and tests showed an abnormal level of a specific protein in her blood. Unfortunately, her condition continued to worsen, leading to the difficult decision to euthanize her. Examination of her tissues showed cancerous cells in various organs, including her bone marrow and lymph nodes. Sadly, the treatment options were not effective, and her health declined significantly.

Abstract

Multiple myeloma was diagnosed in a 22-year-old Arabian mare with a history of chronic weight loss. Quantitative immunoglobulin analysis revealed monoclonal gammopathy (IgG(T), 9,800 mg/dl). Due to progressive weight loss, the horse was euthanatized. Microscopy of tissues revealed plasma cell infiltrates in bone marrow, spleen, pituitary gland, adrenal cortex, muscle of the tongue, and bronchial, renal, and mesenteric lymph nodes.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/3957772/