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Peer-reviewed veterinary case report

Multiple myeloma bone marrow cancer in older cats

By Hanna, Fikry·Published in Journal of feline medicine and surgery·2005·3 Rosebery Avenue, United Kingdom·View original on PubMed

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Original publication title: Multiple myelomas in cats.

Species:
cat

Plain-English summary

A group of nine older cats, all diagnosed with multiple myeloma (a type of bone marrow cancer), were treated over a 16-year period. Most of these cats were around 11 years old, and they received supportive care to keep them hydrated and healthy, along with chemotherapy using melphalan and prednisolone. Out of the eight cats that received chemotherapy, five showed some improvement, with reduced protein levels in their blood. However, the responses were often temporary, and the survival times varied, with some cats living for up to 24 months after treatment.

People also search for: cat multiple myeloma treatment · older cat cancer symptoms · chemotherapy for cats · cat bone marrow cancer prognosis

Abstract

Multiple myelomas are uncommon neoplasms of the bone marrow of cats [Weber NA, Tebeau CS (1998) An unusual presentation of multiple myeloma in two cats. Journal of the American Animal Hospital Association34 (6), 477-483]. Nine cats diagnosed with multiple myelomas were retrospectively identified over a 16-year period (1986-2002). Cats with multiple myelomas were older than 7 years (mean age 11.7 years); six males and three females were affected (2.1), but no breed predisposition was evident. Treatment of multiple myelomas consisted of supportive management in the nine cats and anti-neoplastic therapy in eight cats. Supportive treatment consisted of maintaining hydration, renal function and antimicrobial therapy even when there was no sign of infection. Anti-neoplastic therapy with melphalan and prednisolone was carried out in eight cats. Three failed to respond to treatment and five responded to treatment, but the response was only partial and temporary in one cat. The five cats that responded were improved clinically and had reduced serum protein levels. Five out of eight cats (63%) responded to chemotherapy, and it appeared to be complete in four cats and partial in one cat. Survival time in those cats was 15, 4, 17 and 24 months.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16112593/