Peer-reviewed veterinary case report
Dog with heart inflammation and blood vessel disease
By Torrent, E et al.·Published in The Journal of small animal practice·2005·Department of Animal Medicine and Surgery, Spain·View original on PubMed →
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Original publication title: Myocarditis and generalised vasculitis associated with leishmaniosis in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old female bulldog was brought to the vet because she was very tired, had swollen lymph nodes, and showed signs of eye inflammation. Tests revealed she had a positive result for leishmaniosis, a disease caused by parasites, and she was treated with medications called allopurinol and meglumine antimoniate. Unfortunately, her condition worsened, leading to serious issues like bleeding under the skin, trouble breathing, and ultimately, her heart stopped. A postmortem examination showed severe inflammation in her heart and other organs due to the leishmaniosis infection.
People also search for: bulldog leishmaniosis symptoms · dog heart problems treatment · why is my dog so tired and swollen lymph nodes
Abstract
A three-year-old, female bulldog was presented with bilateral uveitis, apathy, listlessness, generalised lymphadenopathy and perivulvar haematoma. The initial laboratory studies showed non-regenerative anaemia, polyclonal gammopathy and a high urine protein:creatinine ratio. Serology for leishmaniosis was positive and treatment with allopurinol and meglumine antimoniate was started. Despite treatment, the dog's clinical condition deteriorated. Signs included cutaneous ecchymosis, respiratory distress and finally cardiorespiratory arrest. Histopathological studies of postmortem tissue samples revealed a generalised vasculitis of several internal organs and severe myocarditis. Leishmania species organisms were identified in affected tissues using immunoperoxidase labelling and PCR techniques.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16300117/