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Peer-reviewed veterinary case report

Dog with nasal and mouth masses diagnosed with tumor and leishmaniasis

By Levy, Esther et al.·Published in Veterinary clinical pathology·2006·School of Veterinary Medicine·View original on PubMed

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Original publication title: Nasal and oral masses in a dog.

Species:
dog

Plain-English summary

A 5-year-old male stray dog was brought in with serious health issues, including a deformed muzzle, multiple oozing sores, and a fleshy mass in his mouth and nose, along with a discharge from his nose. Tests revealed he had anemia and other blood issues, and further examination showed he had a transmissible venereal tumor (a type of cancer) and leishmaniosis (a parasitic infection). The dog was treated with vincristine and allopurinol, which successfully cleared up his symptoms and the masses.

People also search for: dog nasal mass treatment · dog mouth tumor symptoms · leishmaniosis in dogs · transmissible venereal tumor in dogs

Abstract

A 5-year-old, intact male, stray dog was presented in poor body condition, with pallor, muzzle deformity, multiple oozing fistulas with grass awns, bilateral sanguinopurulent nasal discharge and a fleshy friable mass occupying part of the hard palate. A friable mass occupying both nasal cavities was found on rhinoscopy. The dog had moderate nonregenerative normochromic-microcytic anemia, thrombocytopenia, hyperglobulinemia, and hypoalbuminemia. Cytologic preparations of the nasal and oral masses contained a neoplastic population of round cells with intracytoplasmic and extracellular vacuoles. Leishmania amastigotes also were observed, in the cytoplasm of macrophages and, occasionally, within neoplastic cells. A diagnosis of transmissible venereal tumor and concurrent leishmaniosis was made. Treatment with vincristine and allopurinol resulted in complete resolution of clinical signs and disappearance of the masses. The presence of amastigotes in neoplastic TVT cells may suggest an alternative mode of transmission of canine leishmaniosis where these diseases co-exist.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16511802/