Peer-reviewed veterinary case report
Nasal cavity tumors like rare human COREAH found in 3 dogs
By LaDouceur, E E B et al.·Published in Veterinary pathology·2016·University of California, United States·View original on PubMed →
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Original publication title: Nasal Cavity Masses Resembling Chondro-osseous Respiratory Epithelial Adenomatoid Hamartomas in 3 Dogs.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog, a 10-year-old Beagle, and a 5-year-old Boxer were all brought in for nasal tumors that were causing breathing problems and nasal discharge. Upon examination, veterinarians found masses in their nasal cavities that resembled rare tumors seen in humans. Thankfully, none of the tumors had spread beyond the nasal area, and there was no sign of metastasis. The dogs were treated with surgery to remove the tumors, and they did not show signs of recurrence afterward.
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Abstract
Chondro-osseous respiratory epithelial adenomatoid hamartomas (COREAHs) are rare tumors in the nasal cavity of people, which have not been described in other species. COREAHs in people are minimally invasive and rarely recur following excision. Histologically, these tumors are composed of disorganized, mature, nasal turbinate tissue that is organized into polypoid growths. These growths are lined by respiratory epithelium, contain glandular elements, and are organized around central cores of chondro-osseous matrix. This report describes 3 cases of dogs with nasal tumors that have histomorphology similar to that of COREAH in people. The tumors were all identified within the nasal cavity and were associated with regional bony lysis of the turbinates and surrounding skull bones, a feature that has not been reported in COREAH in people. There was no evidence of metastasis or extension beyond the nasal cavity in any of the 3 cases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26253881/