Peer-reviewed veterinary case report
Nasal granuloma from Scedosporium infection in a young dog
By Cabañes, F J et al.·Published in Journal of clinical microbiology·1998·Hospital Clí, Spain·View original on PubMed →
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Original publication title: Nasal granuloma caused by Scedosporium apiospermum in a dog.
- Species:
- dog
Plain-English summary
A 10-month-old male American Staffordshire terrier was brought to the vet with a 6-month history of a runny nose that had a thick, pus-like discharge. Despite trying antibiotics, the dog showed no improvement. After further tests, the vet discovered a fungal infection caused by Scedosporium apiospermum, which was affecting the dog's nasal cavity. The dog was treated with oral ketoconazole, and during treatment, the nasal discharge improved significantly. This case is notable as it is the first report of this fungus causing nasal issues in dogs.
People also search for: dog nasal discharge treatment · American Staffordshire terrier runny nose · Scedosporium apiospermum in dogs
Abstract
A 10-month-old male American Staffordshire terrier was presented to the Autonomous University of Barcelona Veterinary Teaching Hospital because of a 6-month history of a mucopurulent bilateral nasal discharge. The dog had not responded to antibiotics. A follow-up X ray revealed a mixed pattern of osteolysis and increased radiodensity confined to the nasal cavity. Histologic sections of the biopsy specimens revealed the presence of granules containing numerous septate hyphae that were hyaline to pale brown and smooth, one-celled, subspherical-to-elongate conidia that were hyaline to brownish green, and bacteria. Cultures yielded numerous colonies belonging to Scedosporium apiospermum. Susceptibility tests were performed on the isolated strain. The isolate was sensitive to ketoconazole, intermediate to clotrimazole, and resistant to amphotericin B, 5-fluorocytosine, fluconazole, and itraconazole. The dog was treated with oral ketoconazole. During the treatment a general improvement in the lesions was observed. To our knowledge, S. apiospermum has not been implicated previously as an etiologic agent of nasal disease in dogs. This report provides its first description as such.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9705431/