Peer-reviewed veterinary case report
Nasal tumor with skin spread in an 8-year-old Golden Retriever
By Koehler, J W et al.·Published in Veterinary pathology·2012·Auburn University College of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Nasal tumor with widespread cutaneous metastases in a Golden Retriever.
- Species:
- dog
Plain-English summary
An 8-year-old male Golden Retriever was brought to the vet because he had a mass in his nose and about 30 firm, raised lumps on his skin that were sometimes ulcerated. Tests showed that both the nasal mass and the skin lumps were cancerous, specifically a type of neuroendocrine tumor that had spread from the nose to the skin. This is the first known case of this type of tumor spreading in a dog. Unfortunately, the prognosis for this condition can be serious, and treatment options may be limited.
People also search for: Golden Retriever nasal tumor · dog skin lumps · cancer treatment for dogs
Abstract
An intact, 8-year-old, male Golden Retriever dog was presented for evaluation of a nasal mass and approximately 30 firm, raised, variably ulcerated dermal and subcutaneous masses. Histopathology of both nasal and multiple skin masses revealed multiple nonencapsulated, infiltrative masses comprising clusters, anastomosing trabeculae, and packets of neoplastic, round to ovoid, hyperchromatic cells with marked nuclear molding. Surrounding the neoplastic cells was a marked stromal response in which many of the spindle-shaped cells expressed muscle-specific actin and had ultrastructural features consistent with myofibroblasts. A literature search indicates that this is the first report in a peer-reviewed journal of cutaneous metastasis of a nasal neuroendocrine tumor in any domestic animal species.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21878681/