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Peer-reviewed veterinary case report

Near-infrared imaging helps surgery for fibrosarcoma tumors in cats

By Wenk, Christiane H F et al.·Published in Cancer letters·2013·Institut National de la Sant&#xe9, France·View original on PubMed

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Original publication title: Near-infrared optical guided surgery of highly infiltrative fibrosarcomas in cats using an anti-αvß3 integrin molecular probe.

Species:
cat

Plain-English summary

Twelve cats with aggressive fibrosarcomas (a type of cancer) underwent surgery using a special imaging technique that helps identify tumors more clearly. A special probe was used to make the tumors visible during the operation, ensuring that the surgeons could see and remove all the cancerous tissue without missing any spots. All the cats recovered well after their surgeries, and they are being monitored for long-term health outcomes. This new imaging method shows promise for improving cancer surgery in pets.

People also search for: cat fibrosarcoma treatment · cat cancer surgery recovery · how to detect tumors in cats

Abstract

We investigated how near-infrared imaging could improve highly infiltrative spontaneous fibrosarcoma surgery in 12 cats in a clinical veterinary phase. We used an RGD-based nanoprobe at different doses and times before surgery and a portable clinical grade imaging system. All tumours were labelled by the tracer and had an overall tumour-to-healthy tissue ratio of 14±1 during surgery. No false negatives were found, and the percentage of tumour cells was linearly correlated with the fluorescence intensity. All cats recovered well and were submitted to long-term follow-up that is currently on-going 1year after the beginning of the study.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23200675/