Peer-reviewed veterinary case report
Labrador Retriever with seizures diagnosed with neuronal
By Rossmeisl, John H et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2003·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Neuronal ceroid-lipofuscinosis in a Labrador Retriever.
- Species:
- dog
Plain-English summary
An 8-year-old Labrador Retriever was experiencing partial seizures for 11 months before being examined after death. The findings indicated that the dog had a rare condition called neuronal ceroid-lipofuscinosis (NCL), which is similar to a form of the disease seen in humans. This case is notable as it is the first reported instance of NCL in Labradors. Unfortunately, there was no treatment that could reverse the condition, and the dog’s health declined over time due to the disease.
People also search for: Labrador Retriever seizures · dog neurological disease · canine neuronal ceroid-lipofuscinosis symptoms
Abstract
An 8-year-old Labrador Retriever with an 11-month history of progressive partial seizures and necropsy examination findings characteristic of the lamellar form of canine neuronal ceroid-lipofuscinosis (NCL) is presented. The clinical, light microscopic, and ultrastructural features of this case most closely resemble human adult-onset NCL (Kufs disease). This is the first report of NCL occurring in the Labrador Retriever breed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14535546/