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Peer-reviewed veterinary case report

Cat with T-cell lymphoma causing high eosinophil levels and tissue

By Suzuki, Tamami et al.·Published in The Journal of veterinary medical science·2024·Department of Clinical Sciences, Japan·View original on PubMed

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Original publication title: Nodal T-cell lymphoma with eosinophilic infiltration and sclerosing fibroplasia in a cat with eosinophilia.

Species:
cat
LymphomaStomach & digestionCats

Plain-English summary

An 8-year-old male mixed-breed cat was brought to the vet because of an abdominal mass and high levels of eosinophils (a type of white blood cell). After a thorough examination, it was found that the cat had widespread lymph node enlargement and multiple nodules in the lungs, indicating a serious condition. The diagnosis was T-cell lymphoma, a type of cancer, complicated by eosinophilic infiltration and fibrosis. Unfortunately, this condition can be severe, and the treatment options would depend on the specific circumstances and the vet's recommendations.

People also search for: cat abdominal mass · cat eosinophilia treatment · T-cell lymphoma in cats · cat lung nodules · cat cancer symptoms

Abstract

An 8-year-old castrated male mixed-breed cat presented with an abdominal mass of unknown origin, accompanied by eosinophilia. Autopsy revealed mild-to-severe enlargement of lymph nodes throughout the body and multiple nodules in the lungs. Histopathologically, the lymph nodes showed severe fibroplasia and infiltration by a large number of eosinophils and fewer tumor cells, exhibiting large-sized lymphoid cell morphology. Metastatic lesions of tumor cells with eosinophilic infiltration and fibrosis were observed in the lungs, liver, kidneys, stomach, and intestines. Immunohistochemistry revealed that the tumor cells were positive for CD3 and negative for B cell and mast cell markers. Thus, T-cell lymphoma with eosinophilic infiltration and sclerosing fibroplasia was diagnosed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39443108/