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Peer-reviewed veterinary case report

Nostril mass caused by Leishmania infection in a dog

By Gizzarelli, Manuela et al.·Published in Veterinaria italiana·2018·Department of Veterinary Medicine and Animal Production, Italy·View original on PubMed

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Original publication title: Nostril mass caused by Leishmania spp. in a dog.

Species:
dog

Plain-English summary

A 5-year-old mixed-breed dog was brought in with a mass in its nostril. Although the dog showed no other obvious symptoms, tests revealed it had a mild case of leishmaniasis, a disease caused by a parasite transmitted by sandflies. The vet confirmed the diagnosis by taking a biopsy and finding live parasites. The dog was treated with a combination of medications, miltefosine and allopurinol, and after two months, the mass disappeared and the dog was back to normal.

People also search for: dog nostril mass treatment · leishmaniasis in dogs · nostril tumor in dogs · dog parasite infection symptoms

Abstract

Canine leishmaniasis (CanL) is a systemic zoonotic disease caused by the protozoan Leishmania, an intracellular macrophage parasite, transmitted by the bite of phlebotomine sandflies. In dogs, the clinical disease is mostly characterised by symptoms associated with viscerocutaneous lesions such as lymphadenopathy, splenomegaly, skin lesions, and renal and ocular disease caused by the deposition of immune complexes. The parasite may provoke mucosal lesions which cause atypical clinical signs. The aim of this study is to describe an atypical nostril mass in a dog infected by Leishmania. Clinical examination did not show any systemic clinical signs, while haematological, biochemical, and urinary parameters demonstrated a mild disease stage. Diagnosis was confirmed through the isolation of cultured live parasites by biopsy. The dog was treated with a combination of miltefosine and allopurinol, showing full remission of clinical symptoms after 2 months. The authors outline the importance of considering CanL in the differential diagnosis of mucous and tumour-like lesions.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30575001/