Peer-reviewed veterinary case report
How nutrition and lab tests affect survival in dogs with kidney
By Pedrinelli, Vivian et al.·Published in PloS one·2020·Teaching Veterinary Hospital, Brazil·View original on PubMed →
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Original publication title: Nutritional and laboratory parameters affect the survival of dogs with chronic kidney disease.
- Species:
- dog
Plain-English summary
A group of dogs with chronic kidney disease (CKD) were studied to see how their nutrition and lab test results affected their survival. The researchers found that factors like the stage of the disease, levels of phosphorus and hematocrit (a measure of red blood cells), body condition score, muscle mass, type of food, and appetite all played a role in how long the dogs lived after diagnosis. The study concluded that early diagnosis and a proper renal diet can significantly improve survival rates for dogs with CKD.
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Abstract
Chronic kidney disease is a common disease in dogs, and factors such as serum concentrations of creatinine, albumin, and phosphorus at the moment of diagnosis may influence the survival of these patients. The present retrospective study aimed to evaluate the relationship between survival in dogs with chronic kidney disease and laboratory parameters (creatinine, phosphorus, albumin, and hematocrit) and nutritional parameters (body condition score, muscle mass score, type of food, appetite and feeding method). A total of 116 dogs with chronic kidney disease stages 2 to 4 were included, and survival was calculated considering the time between diagnosis and death. Survival curves were configurated by Kaplan-Meier analysis and a comparison between survival curves was performed by the log-rank test. Factors related to survival were disease stage (p<0.0001), serum phosphorus concentration (p = 0.0005), hematocrit (0.0001), body condition score (p = 0.0391), muscle mass score (p = 0.0002), type of food (p = 0.0009), feeding method (p<0.0001) and appetite (p = 0.0007). Based on data obtained in this study, it is possible to conclude that early diagnosis, as well as nutritional evaluation and renal diet intake, are determinant strategies to increase survival in dogs with chronic kidney disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32603378/