Peer-reviewed veterinary case report
Nutritional and laboratory parameters affect the survival of dogs with chronic kidney disease.
- Journal:
- PloS one
- Year:
- 2020
- Authors:
- Pedrinelli, Vivian et al.
- Affiliation:
- Teaching Veterinary Hospital · Brazil
- Species:
- dog
Plain-English summary
Chronic kidney disease is a common issue in dogs, and this study looked at how certain factors might affect how long dogs live after being diagnosed. Researchers examined 116 dogs with varying stages of the disease and found that things like blood levels of phosphorus and albumin, as well as the dog's body condition and muscle mass, played a significant role in survival. They also noted that the type of food the dog eats and how well it is eating can impact longevity. The findings suggest that catching the disease early and focusing on proper nutrition can help improve survival rates in dogs with chronic kidney disease. Overall, the study concluded that these strategies are important for extending the lives of affected dogs.
Abstract
Chronic kidney disease is a common disease in dogs, and factors such as serum concentrations of creatinine, albumin, and phosphorus at the moment of diagnosis may influence the survival of these patients. The present retrospective study aimed to evaluate the relationship between survival in dogs with chronic kidney disease and laboratory parameters (creatinine, phosphorus, albumin, and hematocrit) and nutritional parameters (body condition score, muscle mass score, type of food, appetite and feeding method). A total of 116 dogs with chronic kidney disease stages 2 to 4 were included, and survival was calculated considering the time between diagnosis and death. Survival curves were configurated by Kaplan-Meier analysis and a comparison between survival curves was performed by the log-rank test. Factors related to survival were disease stage (p<0.0001), serum phosphorus concentration (p = 0.0005), hematocrit (0.0001), body condition score (p = 0.0391), muscle mass score (p = 0.0002), type of food (p = 0.0009), feeding method (p<0.0001) and appetite (p = 0.0007). Based on data obtained in this study, it is possible to conclude that early diagnosis, as well as nutritional evaluation and renal diet intake, are determinant strategies to increase survival in dogs with chronic kidney disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32603378/