Peer-reviewed veterinary case report
Ocular angiosarcoma in four horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1986
- Authors:
- Hacker, D V et al.
- Species:
- horse
Plain-English summary
In a study involving four older horses diagnosed with ocular angiosarcoma, a type of cancer that affects the eye, the tumors started on the surface of the eye and grew slowly. Unfortunately, even after surgical removal and radiation treatment, the cancer spread to other parts of the body. The tumors were found to have two different patterns under the microscope, one with small blood vessel-like structures and another with irregularly shaped cells. A special test was used to confirm the diagnosis by highlighting specific proteins in the tumor tissues. Overall, the treatment did not prevent the cancer from spreading.
Abstract
In 4 horses with ocular angiosarcomas, the common characteristics were that all horses were aged, and the neoplasms developed initially on conjunctival surfaces, grew slowly, and metastasized despite excision and radiation treatment. Histopathologically, the neoplasms were of 2 types: a capillary pattern of scant stroma and endothelial-lined vascular channels, and a solid pattern composed of sheets of pleomorphic cells with hyperchromatic nuclei and poorly defined cytoplasmic borders. Definitive diagnosis was made by use of factor VIII:RAg, which stained the tissues intensely.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/3744979/