Peer-reviewed veterinary case report
Cat with eye tumor causing uveitis and bleeding
By Scurrell, Emma et al.·Published in Veterinary ophthalmology·2013·CytoPath Ltd., United Kingdom·View original on PubMed →
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Original publication title: Ocular histiocytic sarcoma in a cat.
- Species:
- cat
Plain-English summary
A 13-year-old male neutered British Blue cat was brought in with eye problems, including inflammation (uveitis), bleeding (hyphema), and an irregular pupil (dyscoria) in the right eye. Tests showed that the eye had a type of cancer called histiocytic sarcoma, which was also found in skin masses that developed later. Unfortunately, eight months after the eye was removed (enucleation), the cat experienced breathing problems and was euthanized. A postmortem exam revealed multiple tumors in the lungs.
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Abstract
A 13-year-old male neutered British blue cat presented with uveitis, hyphema, and dyscoria in the right eye. Light microscopic examination revealed that the ciliary body, iris root, drainage angle, and adjacent choroid were infiltrated by sheets of large neoplastic mononuclear and multinucleate round to polygonal cells. Neoplastic cells stained immunopositive for CD18 and HLA-DR (MHC class II) and were immunonegative for CD3, CD79a, MUM-1, CD117 (c-Kit), and S100. These findings were consistent with a histiocytic sarcoma. The cat later developed multiple cutaneous masses composed of a similar neoplastic cell population to that seen in the eye. Eight months following enucleation, the cat developed respiratory distress and was euthanized. Postmortem examination revealed multiple pulmonary tumors associated with a pleural effusion.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23683165/