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Peer-reviewed veterinary case report

Eye cancer causing uveitis and bleeding in a cat

By Scurrell, Emma et al.·Published in Veterinary Ophthalmology·2013·CytoPath Ltd. Ledbury Herefordshire HR8 2YD UK, United Kingdom·View original on Crossref

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Original publication title: Ocular histiocytic sarcoma in a cat

Species:
cat

Plain-English summary

A 13-year-old male neutered British Blue cat was brought in with eye problems, including inflammation (uveitis), bleeding (hyphema), and an unusual pupil shape (dyscoria) in the right eye. Tests showed that the eye was affected by a type of cancer called histiocytic sarcoma, which later spread, causing skin lumps and eventually lung tumors. Despite having the affected eye removed, the cat developed breathing problems eight months later and was euthanized due to the progression of the disease.

People also search for: cat eye problems · cat cancer symptoms · British Blue cat respiratory distress · histiocytic sarcoma in cats

Abstract

AbstractA 13‐year‐old male neutered British blue cat presented with uveitis, hyphema, and dyscoria in the right eye. Light microscopic examination revealed that the ciliary body, iris root, drainage angle, and adjacent choroid were infiltrated by sheets of large neoplastic mononuclear and multinucleate round to polygonal cells. Neoplastic cells stained immunopositive for CD18 and HLA‐DR (MHC class II) and were immunonegative for CD3, CD79a, MUM‐1, CD117 (c‐Kit), and S100. These findings were consistent with a histiocytic sarcoma. The cat later developed multiple cutaneous masses composed of a similar neoplastic cell population to that seen in the eye. Eight months following enucleation, the cat developed respiratory distress and was euthanized. Postmortem examination revealed multiple pulmonary tumors associated with a pleural effusion.

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Original publication on Crossref: https://doi.org/10.1111/vop.12052