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Peer-reviewed veterinary case report

Cat with trouble breathing diagnosed with olfactory neuroblastoma

By Parker, Valerie J et al.·Published in Journal of feline medicine and surgery·2010·Iowa State University, United States·View original on PubMed

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Original publication title: Olfactory neuroblastoma in a cat.

Species:
cat

Plain-English summary

A 12.5-year-old male domestic shorthair cat was brought to the vet because he was having trouble breathing. After examining him, the vet suspected a problem in the upper airway, and a CT scan revealed a mass in the nasopharynx. A biopsy confirmed the mass was an olfactory neuroblastoma, a rare type of cancer. Because this tumor is uncommon and treatment options are not well established, the vet discussed potential approaches with the owner. The outcome of the treatment was not detailed in the study, so it's important to consult your vet for the best options.

People also search for: cat breathing problems · olfactory neuroblastoma in cats · cat nasal tumor treatment

Abstract

CASE SUMMARY: A 12.5-year-old castrated male domestic shorthair cat was presented for evaluation of dyspnea. Physical examination suggested upper airway disease. Computed tomography revealed the presence of a nasopharyngeal mass. Biopsies obtained via rhinoscopy led to a diagnosis of olfactory neuroblastoma. CLINICAL CHALLENGES: Olfactory neuroblastoma (or esthesioneuroblastoma) is a rare malignant neoplasm that arises from olfactory neuroepithelium. It was first described in human medicine in 1924. Clinical signs are variable, and diagnosis may prove challenging as this tumor, which is a differential for spontaneous intranasal tumors in cats, may be mistaken for poorly differentiated carcinomas or round cell tumors. Given its rarity, treatment options for this neoplasm have not been thoroughly evaluated and there is no standard treatment protocol. LITERATURE REVIEW: A review of veterinary and human literature is provided, encompassing clinical signs, staging and grading systems, treatment options and prognostic factors.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20974404/