Peer-reviewed veterinary case report
Oncolytic virotherapy of canine and feline cancer.
- Journal:
- Viruses
- Year:
- 2014
- Authors:
- Gentschev, Ivaylo et al.
- Affiliation:
- Department of Biochemistry · Germany
Abstract
Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24841386/