Peer-reviewed veterinary case report
Oral selamectin treats generalised demodicosis in dogs
By Schnabl, B et al.·Published in The Veterinary record·2010·Small Animal Medical Clinic, Germany·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Oral selamectin in the treatment of canine generalised demodicosis.
- Species:
- dog
Plain-English summary
A group of 44 dogs with generalized demodicosis, a skin condition caused by mites, were treated with an oral medication called selamectin. The treatment was given weekly or every other week, and while some dogs experienced side effects like vomiting and diarrhea, the majority tolerated it well. Out of the dogs that completed the study, nine went into remission, all of which had juvenile-onset demodicosis. The study found that dogs with lower clinical scores responded better to the treatment. Overall, selamectin showed promise for treating this condition in dogs.
People also search for: dog skin problems treatment · selamectin for demodicosis · why is my dog itching · dog vomiting after medication · juvenile demodicosis in dogs
Abstract
The success rates and adverse effects of a selamectin spot-on preparation, given orally weekly or every other week, against canine generalised demodicosis were evaluated in 44 dogs, 39 with juvenile-onset demodicosis and five with adult-onset demodicosis. The dogs received selamectin at a dose of 24 to 48 mg/kg once a week, or the same dose every two weeks. Thirty-eight dogs completed the study, four dogs were lost to follow-up and two dogs died. Nine dogs went into remission: all had the juvenile-onset form of the disease. There was no difference between the two treatment groups, but dogs with clinical scores of 65 or less responded significantly better than those with a score of over 65 (P=0.0015). The most frequent adverse effects were vomiting and diarrhoea. Two dogs exhibited mild reversible neurological side effects, which resolved with cessation of treatment. Difficulties in oral administration were observed in several dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20525946/