Peer-reviewed veterinary case report
Rare mouth tumor with two cell types found in a 16-year-old dog
By Muscatello, L V et al.·Published in Journal of comparative pathology·2016·Department of Veterinary Medical Sciences, Italy·View original on PubMed →
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Original publication title: Oral Squamomelanocytic Tumour in a Dog: a Unique Biphasic Cancer.
- Species:
- dog
Plain-English summary
A 16-year-old mixed breed female dog was found to have a multinodular tumor in her gums, which was diagnosed as a squamomelanocytic tumor, a rare type of cancer that involves both skin and pigment cells. The tumor was examined under a microscope to confirm the presence of two types of abnormal cells. Unfortunately, the study does not provide information on treatment or outcome, so it's unclear how the dog responded to this diagnosis. If your dog has a similar growth, it's important to consult your veterinarian for further evaluation and treatment options.
People also search for: dog gum tumor · dog oral cancer treatment · mixed breed dog tumor symptoms
Abstract
In human medicine, squamomelanocytic tumour is a malignant cutaneous neoplasm composed of closely intermingled neoplastic squamous cells and melanocytes. A multinodular gingival tumour in a 16-year-old, mixed breed neutered female dog was examined microscopically. Two populations of neoplastic cells, melanocytic and squamous epithelial cells were intermingled. The melanocytic cells were melan-A positive and cytokeratin AE1-AE3 negative and the squamous component was cytokeratin AE1-AE3 positive and melan-A negative. Bovine papillomavirus was not identified by immunohistochemistry or polymerase chain reaction. A diagnosis of squamomelanocytic tumour was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26805740/