Peer-reviewed veterinary case report
Dog with bone infection and hip pain linked to visceral leishmaniasis
By de Souza, Alda Izabel et al.·Published in Veterinary parasitology·2005·Curso de Medicina Veteriná, Brazil·View original on PubMed →
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Original publication title: Osteolytic osteomyelitis associated with visceral leishmaniasis in a dog.
- Species:
- dog
Plain-English summary
A dog was brought to the vet because it was losing weight and limping on its left back leg. The vet found that the dog had a painful left hip and swollen lymph nodes. Tests revealed that the dog had an infection caused by Leishmania parasites, which led to severe bone damage in the left leg. The vet confirmed the diagnosis through blood tests and tissue samples. Treatment for the infection can help improve the dog's condition, but ongoing care may be needed to manage the effects of the disease.
People also search for: dog limping left leg · weight loss in dogs · Leishmania treatment for dogs
Abstract
A dog was examined with a history of weight loss and lameness of the left hind limb. A painful response to examination of the left hip joint, and lymphadenopathy were noted. Amastigote forms of Leishmania sp. were observed by cytology in samples from the popliteus lymph node, and anti-Leishmania sp. antibodies at a titer of 1:640 were detected in serum by indirect immunofluorescence. Radiological changes included osteolysis and a periosteal proliferative reaction in the left femoral greater trochanter. These changes were histologically characterized as an osteolytic granulomatous osteomyelitis associated with amastigotes within macrophages. Non-decalcified fragments of the periosteum were processed for immunohistochemistry, observed with prominent immunolabelling of amastigotes of Leishmania sp. within macrophages. The diagnosis was further confirmed by positive PCR for Leishmania sp., belonging to the Leishmania donovani complex.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15817202/