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Peer-reviewed veterinary case report

Survival and relapse in dogs with immune-mediated low platelets

By Scuderi, Margaret Ann et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2016·Western College of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Outcome based on treatment protocol in patients with primary canine immune-mediated thrombocytopenia: 46 cases (2000-2013).

Species:
dog

Plain-English summary

A group of 46 dogs diagnosed with immune-mediated thrombocytopenia (a condition where the immune system attacks platelets) were treated with either corticosteroids alone or corticosteroids combined with another therapy. The study found that the type of treatment did not significantly affect whether the dogs survived their hospital stay or experienced a relapse of the condition after discharge. About 39% of the dogs that survived did have a relapse. This suggests that while treatment is necessary, the specific protocol may not greatly influence the overall outcome for these dogs.

People also search for: dog immune-mediated thrombocytopenia treatment · dog platelet count low · corticosteroids for dogs ITP

Abstract

This study investigated the relationship between treatment protocol, survival to discharge, and relapse in 46 dogs diagnosed with primary immune-mediated thrombocytopenia (ITP) at the Western College of Veterinary Medicine between 2000 and 2013. Treatment was at the discretion of the attending clinician and consisted of either a corticosteroid alone or a corticosteroid plus a secondary therapy. There was no association between survival to discharge and treatment protocol (P = 0.23). Of the surviving in-patients, 39% experienced a relapse. Our study failed to show a significant difference in survival and relapse based on treatment protocol.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27152040/