Peer-reviewed veterinary case report
Kidney failure from oxalate buildup in Tibetan Spaniel puppies
By Jansen, J H & Arnesen, K·Published in Journal of comparative pathology·1990·Department of Pathology·View original on PubMed →
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Original publication title: Oxalate nephropathy in a Tibetan spaniel litter. A probable case of primary hyperoxaluria.
- Species:
- dog
Plain-English summary
Two Tibetan Spaniel puppies from the same litter were diagnosed with severe kidney damage caused by a condition called oxalate nephropathy, which is linked to a rare inherited disorder known as primary hyperoxaluria. This condition is unusual in dogs and typically affects humans. Unfortunately, the puppies were found to have end-stage kidney lesions, indicating significant damage. Since this is a serious condition, it's important for pet owners to be aware of the signs of kidney issues in their dogs and consult their veterinarian if they notice any symptoms.
People also search for: Tibetan Spaniel kidney disease · puppy kidney problems · primary hyperoxaluria in dogs
Abstract
Severe oxalate nephropathy with end-stage kidney lesions was found in two pups of a litter of three Tibetan Spaniels. This histopathological finding strongly suggests a primary hyperoxaluria since there was no exposure to agents capable of producing secondary hyperoxaluria. Primary hyperoxaluria has not been reported as a spontaneous disease in the dog, although it is a well-known, but rare, inherited metabolic disease of man.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2394849/