Peer-reviewed veterinary case report
How oxidative stress affects chronic kidney disease in dogs and cats
By Brown, Scott A·Published in The Veterinary clinics of North America. Small animal practice·2008·Department of Small Animal Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Oxidative stress and chronic kidney disease.
Plain-English summary
A dog with chronic kidney disease (CKD) may show symptoms like increased thirst, frequent urination, and weight loss. To help manage this condition, veterinarians often recommend treatments such as specific medications and dietary changes that can reduce oxidative stress in the kidneys. Recent findings suggest that adding certain antioxidants to a dog's diet could be beneficial in slowing the progression of CKD. By using these therapies, many dogs can experience improved kidney function and a better quality of life.
People also search for: dog chronic kidney disease treatment · antioxidants for dogs with kidney disease · managing kidney disease in cats
Abstract
Slowing the rate of progression of chronic kidney disease (CKD) is a critical part of the management of affected dogs and cats. Renal oxidant stress is a previously unrecognized factor in the progression of canine CKD and is likely to be similarly important in feline CKD. Renin-angiotensin antagonism, calcium channel antagonism, n-3 polyunsaturated fatty acid, and antihypertensive and antiproteinuric therapy are commonly recommended for dogs and cats with CKD. These therapies would be expected to reduce renal oxidant stress by decreasing reactive oxygen species generation. Newer data indicate that dietary supplementation with specific antioxidants is an important consideration for limiting renal oxidant stress and progression of CKD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18249247/