Peer-reviewed veterinary case report
Pain relief from radiotherapy for bone cancer in 54 dogs
By Mueller, Fabienne et al.·Published in In vivo (Athens, Greece)·2005·Vetsuisse Faculty·View original on PubMed →
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Original publication title: Palliative radiotherapy with electrons of appendicular osteosarcoma in 54 dogs.
- Species:
- dog
Plain-English summary
Fifty-four dogs with bone cancer (appendicular osteosarcoma) received radiation therapy to help relieve their pain. The treatments involved either three sessions of 8 Gy or four sessions of 6 Gy, and many dogs also received chemotherapy. About 83% of the dogs felt less pain during or after the treatment, with relief lasting an average of 53 days. Both radiation protocols were effective, but adding chemotherapy did not make a difference in pain relief.
People also search for: dog bone cancer treatment · osteosarcoma pain relief in dogs · radiation therapy for dogs with cancer
Abstract
Radiotherapy is effective for the palliation of pain associated with primary and metastatic bony neoplasia in dogs and humans, but no standard treatment protocol has been established. The goal of this study was to evaluate a 3 x 8 Gy and a 4 x 6 Gy protocol using electrons with a betatron or linear accelerator for the treatment of appendicular osteosarcoma in 54 dogs. Thirty-three dogs received chemotherapy consisting of carboplatin IV concurrently with radiotherapy. Eighty-three % (n = 45) of the dogs experienced pain relief during or following treatment. The median duration of pain relief from treatment start was 53 days. In conclusion, both protocols are effective for palliation of clinical signs of canine appendicular osteosarcoma. The outcome reported here is similar to the results of other studies using Co photons. The use of chemotherapy did not improve the response to radiotherapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15999538/