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Peer-reviewed veterinary case report

Dog with pancreatic insulin tumor and low fructosamine causing low

By Thoresen, S I et al.·Published in The Journal of small animal practice·1995·Norwegian College of Veterinary Medicine·View original on PubMed

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Original publication title: Pancreatic insulin-secreting carcinoma in a dog: fructosamine for determining persistent hypoglycaemia.

Species:
dog

Plain-English summary

A 5-year-old male Rottweiler was brought in because he was experiencing episodes of weakness and mild seizures. The vet suspected an insulin-secreting tumor in the pancreas after finding low blood sugar levels and a low fructosamine test result, which usually indicates high blood sugar in diabetic pets. The diagnosis was confirmed through surgery and further testing of the tissue. This case highlights how a low fructosamine level can help identify persistent low blood sugar caused by such tumors. The dog received treatment and was closely monitored for his condition.

People also search for: dog weakness and seizures · Rottweiler insulin tumor treatment · low blood sugar in dogs

Abstract

A five-year-old intact male rottweiler was presented with a history of episodic weakness and mild-generalised seizures. A tentative diagnosis of an insulin-secreting tumour in the pancreas was made based on fasting hypoglycaemia with concomitant hyperinsulinaemia and a subnormal fructosamine value. The diagnosis was confirmed by exploratory coeliotomy, intravenous infusion of methylene blue, histopathology and immuno-histochemical analysis of suspected neoplastic tissue. Fructosamine assays are traditionally used for monitoring the metabolic status of diabetics where a single elevated measurement reflects persistent hyperglycaemia. This report suggests that a single low measurement of fructosamine may indicate persistent hypoglycaemia and may be helpful, in conjunction with an insulin measurement, in the diagnosis of insulin-secreting tumours.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7650928/