Peer-reviewed veterinary case report
Papular skin bumps from Leishmania infection in dogs with immune
By Ordeix, Laura et al.·Published in Veterinary dermatology·2005·Departament de Medicina i Cirurgia Animal, Spain·View original on PubMed →
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Original publication title: Papular dermatitis due to Leishmania spp. infection in dogs with parasite-specific cellular immune responses.
- Species:
- dog
Plain-English summary
Five dogs, including three Boxers and two Rottweilers, were diagnosed with papular dermatitis (raised bumps on the skin) caused by a Leishmania infection. The diagnosis was confirmed through skin tests and examinations. After receiving treatment with a medication called meglumine antimoniate for 3 to 4 weeks, followed by allopurinol for 6 to 10 months, all the dogs returned to normal health. They showed positive immune responses to follow-up tests, indicating that the treatment was effective and the prognosis was good.
People also search for: dog skin bumps treatment · Leishmania infection in dogs · Boxer dermatitis symptoms · Rottweiler skin problems · allopurinol for dog infections
Abstract
Papular dermatitis due to Leishmania spp. infection was diagnosed in three boxers and two Rottweilers with Leishmania-specific cellular immunity. Diagnosis was based on histological and immunohistochemical examination of papules in four dogs and on cytological examination in one dog. Serum protein electrophoresis was within reference ranges and low antibody levels to Leishmania infantum were detected. Delayed-type hypersensitivity (DTH) reaction to leishmanin was evaluated before treatment in three dogs with positive results. After meglumine antimoniate therapy for 3 to 4 weeks and allopurinol treatment for 6 to 10 months, all dogs were clinically normal, had positive DTH reactions to leishmanin and reduced antibody titres. In conclusion, we suggest that this previously unreported cutaneous presentation of canine leishmaniosis appears to be associated with specific immunocompetence and, consequently, with a favourable prognosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15960633/