Peer-reviewed veterinary case report
Skin plaques and early carcinoma linked to papillomavirus
By Kok, Mun Keong et al.·Published in The Journal of veterinary medical science·2019·Graduate School of Agricultural and Life Sciences, Japan·View original on PubMed →
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Original publication title: Pathologic characterization of Felis catus papillomavirus type 5 (FcaPV-5)-associated viral plaques and Bowenoid in situ carcinoma in a Domestic Shorthair cat.
- Species:
- cat
Plain-English summary
A Domestic Shorthair cat was found to have unusual skin growths that were later diagnosed as viral plaques and a type of skin cancer linked to a specific virus called Felis catus papillomavirus type 5 (FcaPV-5). The cat showed signs of skin lesions that were examined under a microscope, revealing changes typical of a viral infection. This case is notable as it is the first reported instance of this virus in a cat in Japan and only the second worldwide. The findings suggest a connection between the virus and the development of skin cancer in cats.
People also search for: cat skin growths · Domestic Shorthair papillomavirus · cat skin cancer treatment · FcaPV-5 in cats · cat viral infection symptoms
Abstract
The present paper describes Felis catus papillomavirus (FcaPV) type 5-associated cutaneous mass in a Domestic Shorthair cat. Histological examination revealed multicentric epidermal acanthosis with papillomavirus-associated cytopathic changes, which progressed to a tumor lobule with intact basement membrane. An association between FcaPV-5 and the cutaneous lesions was confirmed by detection of virus antigen and genes using immunohistochemistry, polymerase chain reaction (PCR), sequencing analysis, and in situ hybridization. Based on these findings, the lesions were diagnosed as FcaPV-5-associated viral plaques and Bowenoid in situ carcinoma (BISC). To date, this is the first reported case of FcaPV-5 infection in a cat in Japan, and the second case reported worldwide. For the first time this papillomavirus type is associated with BISC development.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30905908/