Peer-reviewed veterinary case report
Pentamidine is active in a neutropenic murine model of acute invasive pulmonary fusariosis.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2006
- Authors:
- Lionakis, Michail S et al.
- Affiliation:
- Department of Infectious Diseases · United States
- Species:
- rodent
Abstract
We studied the efficacy of pentamidine (PNT) as prophylaxis or early treatment in acute pulmonary fusariosis in neutropenic mice. PNT-preexposed mice had significantly improved survival and reduced fungal burden compared to amphotericin B-preexposed and untreated mice. PNT-treated mice had increased survival but no difference in fungal burden versus untreated mice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16377700/