Peer-reviewed veterinary case report
Plasma cell tumors around cat ankle joints and outcomes
By Craig, Linden E & Lieske, Danielle E·Published in Veterinary pathology·2022·University of Tennessee, United States·View original on PubMed →
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Original publication title: Periarticular plasma cell tumors in cats.
- Species:
- cat
Plain-English summary
A group of 11 cats with skin tumors around their joints were found to have plasma cell tumors that contained a lot of amyloid, a protein that can complicate diagnosis. Most of these tumors affected the ankle area and could invade deeper tissues, making them more aggressive than similar tumors in dogs. In some cases, the tumors spread to nearby lymph nodes, liver, and spleen. The average survival time for the cats with follow-up information was about 194 days, but it varied widely. Treatment options and outcomes were not detailed, so it's important for pet owners to discuss specific cases with their veterinarian.
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Abstract
This report describes periarticular plasma cell tumors with abundant amyloid in 11 cats. The tarsus was the most commonly affected joint (10/11), and the masses were often circumferential around the tarsal joint, involving the dermis and subcutis. The 2 cases in which synovium was examined had neoplastic cells expanding the synovium. Three of the 5 cases staged radiographically had bony lysis of the affected joint. Cutaneous biopsy specimens often consisted of more amyloid than plasma cells, making the diagnosis difficult on small samples. Follow-up information was available in 7 cases; in those cases, the median survival was 194 days (range 53-671 days). Four cases had confirmed metastases, most often to regional lymph nodes, liver, and spleen. Although canine cutaneous plasma cell tumors are typically benign, those with abundant amyloid surrounding the joints of cats may involve deeper tissues and have a more aggressive behavior. These tumors can be difficult to diagnose due to low cellularity and abundant amyloid.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34763582/