Peer-reviewed veterinary case report
Chihuahua puppy with seizures and brain nodules diagnosis
By Herkommer, Leonie F et al.·Published in Journal of veterinary internal medicine·2020·Institute for Veterinary-Pathology, Germany·View original on PubMed →
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Original publication title: Periventricular nodular heterotopia in a Chihuahua.
- Species:
- dog
Plain-English summary
A 2-month-old female Chihuahua was brought in for having seizures and showing unusual walking and behavior. The vet found signs of a brain issue and did an MRI, which showed multiple nodules in her brain and some swelling. Further tests confirmed that these nodules were a type of brain malformation called periventricular nodular heterotopia, which can lead to seizures. Unfortunately, the condition is serious, and treatment options may be limited, so ongoing management and monitoring will be important for her health.
People also search for: Chihuahua seizures treatment · puppy abnormal behavior · brain malformation in dogs
Abstract
Periventricular nodular heterotopia is a common neuronal malformation in humans, often leading to epilepsy and other neurologic diseases. A 2-month-old female Chihuahua weighing 750 g was examined because of a history of epileptic seizures and abnormalities in gait and behavior. Results of the clinical examination were consistent with a multifocal neurologic disease with localization in the forebrain and spinovestibular system. The magnetic resonance imaging showed multiple bilateral periventricular nodules isointense to gray matter and ventriculomegaly. Histopathological and immunohistological examination of the brain revealed that periventricular nodules consisted of neurons, fewer astrocytes, and some oligodendroglia consistent with periventricular nodular heterotopias.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32445227/