Peer-reviewed veterinary case report
Cat with brain lymphoma spreading around brain ventricles and spinal
By Morita, T et al.·Published in Journal of comparative pathology·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Periventricular spread of primary central nervous system T-cell lymphoma in a cat.
- Species:
- cat
Plain-English summary
A 9-year-old domestic shorthaired cat showed signs of neurological problems and was found to have primary T-cell lymphoma in the brain and spinal cord after a post-mortem examination. The cancer affected areas around the brain's ventricles and caused significant damage to surrounding cells. Unfortunately, this case highlights a serious condition that can occur in cats, and there are no specific treatments mentioned in the study. If your cat is showing neurological symptoms, it's important to consult your veterinarian for a thorough evaluation.
People also search for: cat neurological problems · cat brain cancer symptoms · T-cell lymphoma in cats treatment
Abstract
A 9-year-old domestic shorthaired cat with clinical signs of neurological disease was determined to have primary T-cell lymphoma of the central nervous system (CNS) on necropsy examination. Microscopically, neoplastic lymphocytes were distributed in the CNS parenchyma bilaterally around the cerebral ventricles, third ventricle, mesencephalic aqueduct, fourth ventricle and central canal of the spinal cord. The neoplastic infiltration was associated with complete loss of ependymal cells and marked astrocytosis. A large, solitary neoplastic lesion was present in the parenchyma around the central canal of the spinal cord at the level of the 13th thoracic vertebra. Immunohistochemically, the majority of neoplastic cells expressed CD3 and many also labelled for proliferating cell nuclear antigen (PCNA) and Ki-67. This is, to our knowledge, the first report of periventricular spread of primary CNS T-cell lymphoma in animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19056092/