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Peer-reviewed veterinary case report

Persistent skin leishmaniasis in dogs in São Paulo Brazil

By André Antonio Cutolo et al.·Published in Revista Brasileira de Parasitologia Veterinária·2021·View original on DOAJ

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Original publication title: Persistent cutaneous canine leishmaniasis caused by Leishmania (Viannia) braziliensis in an area with predominance of Nyssomyia neivai in the state of São Paulo, Brazil

Species:
dog

Plain-English summary

A dog in Brazil was diagnosed with a persistent skin infection caused by Leishmania (Viannia) braziliensis, a parasite that can affect both dogs and humans. The dog showed symptoms of skin lesions, and tests confirmed the presence of the parasite. Researchers found that the area was home to a large population of sandflies, which are known to spread this disease. Treatment details were not specified, but the study highlights the importance of monitoring and diagnosing leishmaniasis in dogs, especially in areas where the disease is common.

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Abstract

Abstract American cutaneous leishmaniasis (ACL) is a neglected zoonotic disease caused mainly by Leishmania (Viannia) braziliensis, which is endemic throughout Brazil. Canine ACL cases were investigated in a rural area of Monte Mor, São Paulo, where a human ACL case had been confirmed. Dogs were evaluated through clinical and laboratory diagnosis including serology, cytological tissue preparations and PCR on skin lesions, lymph node and bone marrow samples. Entomological investigations on sandflies trapped in the surroundings of the study area were performed for 14 months. Nyssomyia neivai was the predominant phlebotomine species, comprising 94.65% of the captured specimens (832 out of 879). This species was the most abundant in all trapping sites, including human homes and dog shelters. Ny. whitmani, Migonemyia migonei, Pintomyia monticola, Evandromyia cortellezzii, Pi. fischeri and Expapilata firmatoi were also captured. Two of the three dogs examined were positive for anti-Leishmania IgG in ELISA using the antigen Fucose mannose ligand and skin samples were positive for L. (V.) braziliensis in PCR, but all the samples collected were negative for L. (L.) infantum. One of the dogs had a confirmed persistent infection for more than one year.

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Original publication on DOAJ: https://doi.org/10.1590/s1984-29612021074