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Peer-reviewed veterinary case report

Cat with permethrin poisoning developed lasting blood fat and eye

By Seitz, Marc A & Burkitt-Creedon, Jamie M·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2016·Emergency Department·View original on PubMed

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Original publication title: Persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy in a cat with permethrin toxicosis.

Species:
cat

Plain-English summary

A 5-year-old female domestic short-haired cat was treated for severe poisoning after exposure to permethrin, a common insecticide. The vet used a high dose of intravenous lipid therapy to help the cat recover, but this led to a condition called gross lipemia, where the blood became cloudy due to fat particles, lasting for at least 48 hours. Additionally, the cat showed signs of corneal lipidosis, which is a buildup of fat in the eye, but this cleared up within a week. Overall, the cat improved after treatment, but the side effects highlight the experimental nature of this therapy in cats.

People also search for: cat permethrin poisoning treatment · cat eye problems after treatment · intravenous lipid therapy side effects in cats

Abstract

OBJECTIVE: To describe the observation of persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy (IVLT) in a cat with permethrin toxicosis. CASE SUMMARY: A 5-year-old, spayed female, domestic short-haired cat with permethrin toxicosis was treated with a high dose of IVLT as an adjunct treatment when it remained severely obtunded following traditional supportive care. The cat received intravenous 20% lipid emulsion as a 1.5 mL/kg bolus given over 10 minutes followed by a constant rate infusion of 0.25 mL/kg/min for 2 hours. The cat developed gross lipemia that persisted at least 48 hours after the single dose of IVLT. Changes consistent with corneal lipidosis were observed and resolved within 1 week after IVLT. NEW OR UNIQUE INFORMATION PROVIDED: This is the first report documenting the complications of persistent gross lipemia and suspected corneal lipidosis in a cat following IVLT. This report underscores the off-label, experimental nature of IVLT as a treatment for intoxication in cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26748969/