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Peer-reviewed veterinary case report

Phase II clinical trial of combination chemotherapy with dexamethasone for lymphoma in dogs.

Journal:
Journal of the American Animal Hospital Association
Year:
2007
Authors:
Greenberg, Chelsea B et al.
Affiliation:
Department of Veterinary Clinical Sciences · United States
Species:
dog

Abstract

Dogs with histologically confirmed lymphoma were treated with a 14-week induction chemotherapy protocol that included dexamethasone. A phase II clinical trial was done using a standard two-stage design. Complete remission occurred in 21 (88%) dogs, with a median initial progression-free interval of 186 days. Toxicity was mild and self-limiting in the majority of dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17209082/