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Peer-reviewed veterinary case report

Dog lymphoma treated with chemo and dexamethasone shows high remission

By Greenberg, Chelsea B et al.·Published in Journal of the American Animal Hospital Association·2007·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Phase II clinical trial of combination chemotherapy with dexamethasone for lymphoma in dogs.

Species:
dog

Plain-English summary

A group of dogs diagnosed with lymphoma (a type of cancer) underwent a 14-week chemotherapy treatment that included a medication called dexamethasone. Out of the dogs treated, 21 of them, or 88%, went into complete remission, meaning their cancer was no longer detectable. The dogs experienced mild side effects that mostly went away on their own. This treatment helped many dogs feel better and live longer without the cancer progressing for an average of about 186 days.

People also search for: dog lymphoma treatment · dexamethasone for dogs · dog cancer remission rates

Abstract

Dogs with histologically confirmed lymphoma were treated with a 14-week induction chemotherapy protocol that included dexamethasone. A phase II clinical trial was done using a standard two-stage design. Complete remission occurred in 21 (88%) dogs, with a median initial progression-free interval of 186 days. Toxicity was mild and self-limiting in the majority of dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17209082/