Peer-reviewed veterinary case report
Phenobarbital-responsive sialadenosis in dogs: case series.
- Journal:
- Topics in companion animal medicine
- Year:
- 2014
- Authors:
- Alcoverro, Emili et al.
- Affiliation:
- Hospital Clinic Veterinari Fundation · Spain
- Species:
- dog
Plain-English summary
Phenobarbital-responsive sialadenosis (PRS) is a rare condition in dogs where the salivary glands become enlarged without a known cause. In a study of four dogs with this condition, common symptoms included vomiting, retching, and gulping, along with swelling of the glands under the jaw. Since there isn't a specific test for PRS, veterinarians need to conduct a thorough examination to rule out other possible causes of chronic vomiting. The diagnosis is usually confirmed when the dogs show a quick and significant improvement after starting treatment with phenobarbital. In this case series, the treatment was effective for the dogs involved.
Abstract
Phenobarbital-responsive sialadenosis (PRS) is a rare idiopathic disease in dogs. Vomiting, retching, and gulping with bilateral enlargement of the submandibular salivary glands are the more frequent clinical signs. A thorough diagnostic examination must be performed to rule out the most important systemic etiologies involved with chronic vomiting, as there is no specific test to diagnose PRS. Diagnosis is confirmed clinically by a rapid and dramatic improvement of clinical signs after instauration of phenobarbital treatment. The aim of this article is to describe the clinical presentation, diagnostic findings, and outcome of a case series of 4 dogs with presumptive PRS.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25813851/