Peer-reviewed veterinary case report
Dog vomiting from salivary gland issue and esophagus narrowing
By Chae, Hyung-Kyu et al.·Published in Veterinary medicine and science·2021·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Successful treatment of a dog with phenobarbital-responsive sialadenosis and an oesophageal stricture.
- Species:
- dog
Plain-English summary
An 8-year-old neutered male Pomeranian was brought in for vomiting that had been ongoing for two years. The dog was diagnosed with a condition called phenobarbital-responsive sialadenosis, which caused nausea and salivary gland enlargement. While treatment with phenobarbital initially helped, the vomiting returned when the medication was stopped. Further investigation revealed an esophageal stricture, which was treated with balloon dilation. After three dilation procedures, the dog’s vomiting stopped, and he was able to eat comfortably again without recurrence of symptoms.
People also search for: Pomeranian vomiting treatment · dog esophageal stricture symptoms · phenobarbital for dogs vomiting
Abstract
BACKGROUND: Phenobarbital-responsive sialadenosis (PRS) can cause nausea and vomiting, and is rarely reported in dogs. OBJECTIVES: An 8-year-old neutered, male Pomeranian dog was presented to our teaching hospital with vomiting that began 2 years ago. The clinical signs repeatedly improved and deteriorated despite treatment. METHODS: The only abnormality found on physical examination was salivary gland enlargement, and no specific findings were observed on blood analysis and imaging tests. The results of the fine needle aspirate cytology from the salivary glands revealed possible sialadenosis. Phenobarbital was prescribed, and the patient's symptoms resolved. However, upon discontinuing drug, the patient's clinical signs recurred and did not improve even after re-introduction of phenobarbital and the addition of other anticonvulsant drugs. An oesophageal stricture was observed on an oesophagram, and fibrosis was confirmed endoscopically. A balloon dilation was performed to expand the stenosis. RESULTS: After the first procedure, the patient's clinical signs initially improved, but relapsed 2 weeks later. A total of three oesophageal dilation procedures were performed using a sequentially larger diameter balloon. After the third procedure, the patient's clinical signs were managed without recurrence. The cause of recurrent gastrointestinal signs following the initial successful treatment of phenobarbital-responsive sialadenosis was due to oesophageal stricture formation. CONCLUSIONS: This case report demonstrates the successful management of PRS with subsequent oesophageal stricture formation in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33410603/