Peer-reviewed veterinary case report
Photodynamic therapy for intranasal tumors in dogs and cats
By Lucroy, Michael D et al.·Published in Journal of veterinary internal medicine·2003·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Photodynamic therapy for the treatment of intranasal tumors in 3 dogs and 1 cat.
Plain-English summary
A 7-year-old dog, a 10-year-old dog, a 12-year-old dog, and a 5-year-old cat were treated for intranasal tumors using a special light therapy called photodynamic therapy (PDT). After the treatment, all pets experienced some facial swelling, but it went away within three days. They also showed improvements in symptoms like nosebleeds, sneezing, and nasal discharge. While the effects lasted for different lengths of time, two of the pets had results similar to those seen with radiation therapy. This treatment was well tolerated, suggesting it could be a good option for managing these types of tumors in pets.
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Abstract
Three dogs and 1 cat with intranasal tumors were treated with pyropheophorbide-a-hexyl ether-based photodynamic therapy (PDT). PDT was well tolerated by all the animals, and no adverse effects from photosensitizer injection, such as cutaneous photosensitization, were observed. Facial swelling was observed in all animals after each PDT treatment but resolved spontaneously within 72 hours after treatment. All animals had a decrease in severity of epistaxis, frequency of sneezing, and amount of nasal discharge after PDT. Clinical signs were controlled for variable time, although long-term responses were comparable with radiation therapy in 2 animals. This small case series demonstrates another application for PDT in veterinary medicine. On the basis of these findings. further studies are warranted to define the role of PDT in the management of intranasal tumors in dogs and cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14529144/