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Peer-reviewed veterinary case report

Dog with placentitis and leishmaniasis causing abortion

By Dubey, J P et al.·Published in Journal of the American Veterinary Medical Association·2005·Animal and Natural Resources Institute, United States·View original on PubMed

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Original publication title: Placentitis associated with leishmaniasis in a dog.

Species:
dog

Plain-English summary

A 1.5-year-old Coonhound in Maryland had a serious issue when she aborted seven puppies. A vet examined the placenta and found signs of placentitis, which is inflammation of the placenta, caused by an infection with Leishmania parasites. Tests confirmed the presence of these parasites in the placenta but not in the puppies themselves. The dog was diagnosed with leishmaniasis, a disease caused by these parasites, and further tests showed a positive result for the infection.

People also search for: dog abortion causes · Coonhound leishmaniasis symptoms · placentitis in dogs treatment

Abstract

A 1.5-year-old Coonhound from Maryland aborted 7 fetuses. Placenta and internal tissues of 1 fetus were examined histologically. The predominant lesion was placentitis characterized by necrosis and infiltration of mixed leukocytes. Numerous Leishmania spp amastigotes were identified in placental trophoblasts, and the diagnosis was confirmed by use of immunohistochemical staining with Leishmania-specific antibodies. Protozoa were not found in the fetal tissues. An indirect fluorescent antibody test yielded a serum titer of 1:100, and a recombinant K39 immunoassay of serum yielded positive results for the K39 Leishmania antigen.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16266015/