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Peer-reviewed veterinary case report

Placentitis associated with leishmaniasis in a dog.

Journal:
Journal of the American Veterinary Medical Association
Year:
2005
Authors:
Dubey, J P et al.
Affiliation:
Animal and Natural Resources Institute · United States
Species:
dog

Abstract

A 1.5-year-old Coonhound from Maryland aborted 7 fetuses. Placenta and internal tissues of 1 fetus were examined histologically. The predominant lesion was placentitis characterized by necrosis and infiltration of mixed leukocytes. Numerous Leishmania spp amastigotes were identified in placental trophoblasts, and the diagnosis was confirmed by use of immunohistochemical staining with Leishmania-specific antibodies. Protozoa were not found in the fetal tissues. An indirect fluorescent antibody test yielded a serum titer of 1:100, and a recombinant K39 immunoassay of serum yielded positive results for the K39 Leishmania antigen.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16266015/