Peer-reviewed veterinary case report
Platelet-rich Plasma Combined With a Sterile 3D Polylactic Acid Scaffold for Postoperative Management of Complete Hoof Wall Resection for Keratoma in Four Horses.
- Journal:
- Journal of equine veterinary science
- Year:
- 2020
- Authors:
- Leonardi, Fabio et al.
- Affiliation:
- Department of Veterinary Science · Italy
- Species:
- horse
Plain-English summary
In this study, four horses with a noncancerous tumor called a keratoma, which was causing them to limp, had surgery to remove the affected part of their hoof. After the surgery, the wounds were treated with a special mixture of their own blood (platelet-rich plasma) and a safe, three-dimensional material to help healing. The treatment was done several times over the following weeks, and by 6 to 21 days after surgery, healthy tissue started to grow back. Within 6 to 8 months, the horses had completely healed, their hooves were restored, and they were able to return to their normal activities without any further limping.
Abstract
Keratoma is a nonmalignant horse tumor that grows in the space between the horn of the hoof and the distal phalanx. Keratoma causes lameness in the horse, and surgical excision is the treatment of choice. Four horses underwent removal of a keratoma by complete hoof wall resection. The remaining wound was treated with platelet-rich plasma (PRP) combined with a sterile three-dimensional polylactic acid scaffold. The PRP was applied at 3, 6, 9, 12, 15, and 18 days postoperatively. The surgical site was cleaned with gauzes and swabs soaked in Ringer's lactate solution before applying PRP and the foot bandage. Healthy granulation tissue developed at 6-21 days postoperatively. The hoof wall defect was completely filled with new hoof wall within 6-8 months after surgery. All horses returned to their previous exercise level, and no recurrence of lameness was reported by the owner.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32797800/