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Peer-reviewed veterinary case report

Pop-Out Myocardial Infarction Induction in Mice.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2024
Authors:
Wang, Bingyan J & Chaudhry, Hina W
Affiliation:
Icahn School of Medicine at Mount Sinai · United States
Species:
rodent

Abstract

Myocardial infarction (MI) in mice is a widely used surgical model in preclinical cardiac repair studies to recapitulate human cardiovascular ischemic disease. Induction of reproducible infarct size is crucial for quantitative and analytical purpose. Here we describe a quick and reliable method to induce consistent infarct size in mice in less than a minute.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38676890/