Peer-reviewed veterinary case report
Dog with seizures caused by brain porencephaly and cortical dysplasia
By G. Machado et al.·Published in BMC Veterinary Research·2012·View original on Semantic Scholar →
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Original publication title: Porencephaly and cortical dysplasia as cause of seizures in a dog
- Species:
- dog
Plain-English summary
A one-year-old male Shih Tzu was brought to the vet for abnormal walking and seizures. The dog experienced generalized tonic-clonic seizures, which are severe convulsions. After examining the brain, the vet found a rare condition called porencephaly, where a cleft in the brain created an abnormal connection between spaces in the brain, along with other brain abnormalities. Unfortunately, due to the severity of the condition, the dog did not recover.
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Abstract
BackgroundSeizures are a common problem in small animal neurology and it may be related to underlying diseases. Porencephaly is an extremely rare disorder, and in Veterinary Medicine it affects more often ruminants, with only few reports in dogs.Case presentationA one-year-old intact male Shih-Tzu dog was referred to Veterinary University Hospital with history of abnormal gait and generalized tonic-clonic seizures. Signs included hypermetria, abnormal nystagmus and increased myotatic reflexes. At necropsy, during the brain analysis, a cleft was observed in the left parietal and occipital lobes, creating a communication between the subarachnoid space and the left lateral ventricle, consistent with porencephaly; and also a focal atrophy of the caudal paravermal and vermal portions of the cerebellum. Furthermore, the histological examination showed cortical and cerebellar neuronal dysplasia.ConclusionsReports of seizures due to porencephaly are rare in dogs. In this case, the dog presented a group of brain abnormalities which per se or in assemblage could result in seizure manifestation.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/23269021