Peer-reviewed veterinary case report
Porencephaly and hippocampal shrinkage linked to seizures in dogs
By Hori, Ai et al.·Published in The Journal of veterinary medical science·2015·Department of Small Animal Clinical Sciences, Japan·View original on PubMed →
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Original publication title: Porencephaly in dogs and cats: relationships between magnetic resonance imaging (MRI) features and hippocampal atrophy.
Plain-English summary
A 2-year-old mixed-breed dog and a 5-year-old cat were both diagnosed with porencephaly, a rare brain defect that can cause seizures. Both pets showed signs of seizures and had brain imaging that revealed atrophy (shrinkage) of the hippocampus, an area of the brain involved in memory and seizure control. The severity of their seizures seemed to be related to the size of the brain cysts and the extent of the hippocampal atrophy. Unfortunately, the study did not provide specific treatments or outcomes for these pets, but it highlights the importance of MRI in diagnosing and understanding this condition.
People also search for: dog seizures causes · cat brain problems · porencephaly in pets · MRI for dog seizures · treatment for cat seizures
Abstract
Porencephaly is the congenital cerebral defect and a rare malformation and described few MRI reports in veterinary medicine. MRI features of porencephaly are recognized the coexistence with the unilateral/bilateral hippocampal atrophy, caused by the seizure symptoms in human medicine. We studied 2 dogs and 1 cat with congenital porencephaly to characterize the clinical signs and MRI, and to discuss the associated MRI with hippocampal atrophy. The main clinical sign was the seizure symptoms, and all had hippocampal atrophy at the lesion side or the larger defect side. There is association between hippocampal atrophy or the cyst volume and the severe of clinical signs, and it is suggested that porencephaly coexists with hippocampal atrophy as well as humans in this study.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25786357/