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Peer-reviewed veterinary case report

Preclinical efficacy of anecortave acetate.

Journal:
Survey of ophthalmology
Year:
2007
Authors:
Clark, Abbot F
Affiliation:
Discovery Research · United States

Abstract

Anecortave acetate is a unique ocular angiostatic cortisene that has broad-based anti-angiogenic activity in 14 different preclinical models of neovascularization, across multiple species and inducers of neovascularization. Anecortave acetate is being tested clinically for inhibition of choroidal neovascularization associated with age-related macular degeneration.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17240256/