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Peer-reviewed veterinary case report

Dog with immune anemia and low platelets treated with prednisolone

By Holloway, S A et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Prednisolone and danazol for treatment of immune-mediated anemia, thrombocytopenia, and ineffective erythroid regeneration in a dog.

Species:
dog

Plain-English summary

An 8-year-old spayed Miniature Schnauzer was brought to the vet because she had low red blood cell and platelet counts, which can cause weakness and bleeding problems. Tests showed that her bone marrow wasn't producing enough healthy red blood cells. The vet treated her with a blood transfusion, a steroid called prednisolone, and a medication called danazol, which helped her condition stabilize and allowed her body to start producing new red blood cells again.

People also search for: dog low red blood cell treatment · Miniature Schnauzer anemia symptoms · prednisolone for dog anemia

Abstract

Immune-mediated anemia and thrombocytopenia were diagnosed in an 8-year-old spayed Miniature Schnauzer. The initial CBC indicated poor erythroid regeneration and concurrent leukopenia. The results of a Coombs test and ANA titer were strongly positive. Examination of a bone marrow specimen revealed erythrophagocytosis and a maturation arrest in the RBC series. Treatment with transfusion plus prednisolone and an attenuated androgen (danazol) resulted in stabilization of the PCV and the development of reticulocytosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2243038/