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Peer-reviewed veterinary case report

Presence of Gumprecht shadows (smudge cells) in bovine leukemia virus-positive cattle.

Journal:
Journal of virological methods
Year:
2013
Authors:
Panei, Carlos Javier et al.
Affiliation:
Faculty of Veterinary Sciences

Abstract

Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple artifacts of slide preparation, but ragged lymphoid cells found mainly in peripheral blood smears from human patients with chronic lymphocytic leukemia. In this study, we report the presence of Gumprecht shadows in peripheral blood from BLV-positive cattle.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23886563/