Peer-reviewed veterinary case report
Presumed masitinib-induced nephrotic syndrome and azotemia in a dog.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2016
- Authors:
- Devine, Lauren & Polzin, David J
- Affiliation:
- North Carolina State Veterinary Hospital - Internal Medicine · United States
- Species:
- dog
Abstract
Masitinib mesylate is a tyrosine-kinase inhibitor approved for the treatment of nonresectable or recurrent, Grade 2 or 3 mast cell tumors in dogs. This report describes nephrotic syndrome and acute kidney injury attributed to masitinib and illustrates the need for regular monitoring of serum creatinine concentration, urinalysis, and urine protein:creatinine ratio during its use.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27429464/