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Peer-reviewed veterinary case report

Cat with eye tumor and lung spread after injury

By Moreira, Matheus V L et al.·Published in Veterinary ophthalmology·2018·Department of Clinics and Surgery, Brazil·View original on PubMed

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Original publication title: Presumed post-traumatic ocular chondrosarcoma with intrathoracic metastases in a cat.

Species:
cat

Plain-English summary

A 5-year-old spayed female domestic shorthair cat was brought in for a check-up because she was having problems with her left eye, which was diagnosed with a tumor that caused glaucoma and blindness. The vet removed the eye to examine the tumor, which turned out to be a type of cancer called chondrosarcoma. Unfortunately, six months later, the cat died due to breathing problems caused by the cancer spreading to her lungs and other areas in her chest. This case is significant because it is the first known instance of this type of eye cancer spreading in cats.

People also search for: cat eye tumor treatment · cat glaucoma symptoms · chondrosarcoma in cats · cat breathing problems after surgery

Abstract

An indoor-only, 5-year-old, spayed female domestic shorthair cat presented for an ophthalmic examination of the left eye. An intraocular tumor with secondary glaucoma and blindness was diagnosed; the globe was enucleated and sent for histopathological examination. Gross examination revealed a solid white mass filling the entire vitreous space and replacing the iris and ciliary body. The lens and retina appeared to be similarly replaced by the neoplasm. Histological examination revealed a complete loss of the internal ocular structures, with a ruptured capsule as the only remnant of the lens within an extensive malignant mesenchymal neoplastic cell proliferation. The cells were polygonal, with well-defined cytoplasmic borders and abundant weakly basophilic cytoplasm, embedded within the islands of chondroid matrix. No neoplastic invasion of the sclera was apparent. The animal died 6 months after the enucleation due to respiratory distress. Gross examination revealed numerous firm, white to tan nodular masses with smooth to mildly irregular surfaces dispersed throughout the parietal pleura, thoracic surface of the diaphragm, tracheobronchial and mediastinal lymph nodes, pericardium, and lungs. On cross-section, the neoplastic nodules were solid and variably translucent, resembling hyaline cartilage. Histologically, these nodules were similar to the neoplasm identified earlier in the left globe. Metastasis of post-traumatic ocular chondrosarcoma has not yet been described in cats. This is therefore believed to be the first report of metastases of this type of neoplasm in cats. This case adds to the limited set of data on the outcome of this type of tumor.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28972682/