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Peer-reviewed veterinary case report

Prevalence of anterior uveitis in cases of systemic inflammatory response syndrome in dogs and cats.

Journal:
Veterinary ophthalmology
Year:
2025
Authors:
Fortuny-Clanchet, Marc et al.
Affiliation:
Hospital Veterinari Canis · Spain

Plain-English summary

A study looked at how common anterior uveitis (an eye condition) is in dogs and cats that were hospitalized with systemic inflammatory response syndrome (SIRS), a serious condition that can affect the whole body. They examined 42 animals with SIRS and 26 without it. They found that 38% of the animals with SIRS developed anterior uveitis, compared to only 7.7% of those without SIRS. This suggests that if your pet has SIRS, it’s important for the vet to check their eyes as well. The study concluded that anterior uveitis is more common in pets with SIRS.

Abstract

OBJECTIVE: To determine the prevalence of anterior uveitis in dogs and cats hospitalized with a diagnosis of systemic inflammatory response syndrome (SIRS). ANIMALS STUDIED: Dogs and cats hospitalized between May 2020 and January 2021 were prospectively included. PROCEDURES: Patients were categorized into two different groups: The first group included patients diagnosed with SIRS, and the second group included patients hospitalized without SIRS as a control group. Daily physical and ophthalmological examinations were conducted during hospitalization. Diagnosis of anterior uveitis was made based on the presence of aqueous flare, low intraocular pressure, and other associated ocular signs such as episcleral injection and miosis. A multinomial logistic regression analysis was conducted to investigate factors associated with SIRS and anterior uveitis development. RESULTS: The study comprised 42 patients with SIRS and 26 patients without SIRS. Among those with SIRS, 38% developed anterior uveitis, whereas only 7.7% of patients without SIRS showed signs of anterior uveitis. The prevalence of uveitis was significantly higher in animals with SIRS compared to those without SIRS (p&#x2009;<&#x2009;.05). CONCLUSION: Anterior uveitis is more prevalent in patients with SIRS than patients without SIRS. Therefore, complete ophthalmic examination is recommended in all patients presenting with this syndrome.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38701003/