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Peer-reviewed veterinary case report

Dog with skin fungal infection and reaction to itraconazole treatment

By Plotnick, A N et al.·Published in Journal of the American Animal Hospital Association·1997·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog.

Species:
dog

Plain-English summary

A 13-month-old female Labrador retriever developed draining sores on her right back leg three weeks after a trip to Arizona. She was diagnosed with a fungal skin infection called coccidioidomycosis. Initially, the vet treated her with itraconazole, but this made her condition worse due to a drug reaction. After stopping the itraconazole, her symptoms improved, and she was successfully treated with ketoconazole, which cleared the fungal infection.

People also search for: dog skin sores after travel · Labrador coccidioidomycosis treatment · dog itraconazole side effects · fungal skin infection in dogs · ketoconazole for dog skin problems

Abstract

Three weeks after traveling to Arizona, a 13-month-old, female Labrador retriever developed draining tracts in the right hind limb. Primary cutaneous coccidioidomycosis was diagnosed. Initial treatment with itraconazole resulted in exacerbation of clinical signs. Histopathology was suggestive of a cutaneous drug eruption. Discontinuation of the itraconazole caused resolution of the drug eruption. Successful treatment of the fungal infection was achieved using ketoconazole.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9111724/