Peer-reviewed veterinary case report
Gastrointestinal lymphoma causing vomiting and weight loss
By Steinberg, H et al.Ā·Published in Veterinary pathologyĀ·1995Ā·Department of Pathobiological Sciences, United StatesĀ·View original on PubMed ā
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Original publication title: Primary gastrointestinal lymphosarcoma with epitheliotropism in three Shar-pei and one boxer dog.
- Species:
- dog
Plain-English summary
A 4-year-old male Shar-pei, a 7-year-old male Shar-pei, a 7-year-old male Shar-pei, and a 7-year-old female Boxer were brought in for severe diarrhea, vomiting, weight loss, and lack of appetite over several weeks. They were also very lethargic and had lost a significant amount of weight. After examining their stomachs with an endoscope and taking biopsies, the vets found cancerous cells in their stomach and intestines. Unfortunately, all three dogs were diagnosed with a type of cancer called lymphoma, which affected their stomach and intestines, and they did not survive.
People also search for: dog vomiting weight loss Ā· Shar-pei diarrhea treatment Ā· Boxer lymphoma symptoms
Abstract
Three male Shar-pei dogs and one female spayed Boxer dog ranging in age from 4 years, 4 months to 7 years, 8 months had 4-7-week histories of diarrhea, progressive anorexia, weight loss, and vomiting. The dogs were depressed, lethargic, and hypoalbuminemic, with losses of 23-39% of body weight. Endoscopic examination revealed gastric ulceration with areas of mucosal hyperemia and pallor. Small nodules with occasional central depressions were present in three dogs. Gastric and proximal duodenal mucosal biopsies showed neoplastic lymphocytes infiltrating the lamina propria, with invasion of the superficial and glandular epithelial basement membrane. Immunohistochemical evaluation of two dogs was negative for anti-canine IgG and positive for anti-CD3. Necropsy of the Boxer and two Shar-peis confirmed epitheliotropic gastric and small intestinal lymphoma in all three dogs, with mesenteric lymph node and hepatic involvement in two and one dog, respectively.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7483219/